Codeine, the active ingredient in codeine phosphate, is a so-called analgesic, a medicine designed to relieve pain. Codeine decreases pain signals or stops them from reaching the brain, thus reducing or eliminating pain
Codeine phosphate is an analgesic indicated for the relief of mild to moderate pain.
DOSAGE AND ADMINISTRATION
For Analgesia: Dosage should be adjusted according to the severity of the pain and the response of the patient.
Adults: 15 to 60 mg every 4 to 6 hours (usual adult dose, 30 mg).
Children: 1 Year of Age and Older – 0.5 mg/kg of b.d. weight or 15 mg/m2 of b.d. surface every 4 to 6 hours.
Soluble tablets codeine phosphate are administered subcutaneously or intramuscularly.
Solutions for injection should be prepared with sterile water and filtered through a 0.22 membrane filter.
Note: Do not use the solution if it is more than slightly discolored or contains a precipitate.
Codeine Phosphate Side effects
The most frequent adverse reactions include lightheadedness, dizziness, sedation, nausea, and vomiting. These effects seem to be more prominent in ambulatory than in non ambulatory patients, and some of these adverse reactions may be alleviated if the patient lies down.
Other adverse reactions include euphoria, dysphoria, constipation, and pruritus.